Stem cell factor and IgE-stimulated murine mast cells produce chemokines (CCL2, CCL17, CCL22) and express chemokine receptors
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چکیده
منابع مشابه
The role of chemokines and chemokine receptors in mycosis fungoides
Background: Chemokines are a family of cytokines initially characterized by their capacity to induce chemotaxis, or directed leukocyte migrations. These receptors are activated by chemotactic cytokines called chemokines. Interactions between chemokines and chemokine receptors also are involved in tumorigenesis, migration and invasion of lymphoma cells.Methods: An English literature search...
متن کاملChemokines and chemokine receptors in stem cell circulation.
Stem cells are rare, pluripotent, self-renewing cells that give rise to all mature cells during development and adult life. Due to their proliferative capabilities and their ability to home and contribute to the regeneration of damage tissue, stem cells can be transformed into established tumors. Stem cells can function as a double-edged sword--they have the ability to circulate and migrate thr...
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In response to IgE and specific multivalent antigen, mast cell lines (both growth factor-dependent and -independent) induce the transcription and/or secretion of a number of cytokines having a wide spectrum of activities. We have identified IL-1, IL-3, IL-5, IL-6, IFN-gamma, GM-CSF, JE, MIP1 alpha, MIP1 beta, and TCA3 RNA in at least two of four mast cell clones. The production of these product...
متن کاملChemokines and Chemokine Receptors
Chemokines (CKs) are a family of small proteins secreted by a great variety of cell types. Their name (derived from chemoattractant cytokines) is due to their ability to induce directed chemotaxis in nearby responsive cells. Some CKs are considered pro-inflammatory and can be induced during an immune response to promote cells of the immune system to a site of infection, whereas others are consi...
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BACKGROUND Idiopathic pulmonary fibrosis (IPF) is a chronically progressive interstitial lung disease of unknown etiology. Previously, we have demonstrated the selective upregulation of the macrophage-derived chemokine CCL22 and the thymus activation-regulated chemokine CCL17 among chemokines, in a rat model of radiation pneumonitis/pulmonary fibrosis and preliminarily observed an increase in b...
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ژورنال
عنوان ژورنال: Inflammation Research
سال: 2001
ISSN: 1023-3830,1420-908X
DOI: 10.1007/s000110050741